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Mapping DNA lesions offers new strategies for understanding genotoxicity and changes in the cellular microenvironment

10-23-26 - 12:00pm to 10-23-26 - 1:00pm
Speaker(s)
Natalie Gassman, PhD, University of Alabama at Birmingham
Contact
Straehle, Jessica
Phone
919-613-8078
Email
jessica.straehle@duke.edu

Dr. Gassman's talk is going to explore the use of a novel DNA damage assessment method to understand DNA damage and repair defects caused by exogenous agents and how persistent DNA damage changes cells and their microenvironment, particularly in the context of cancer.

Natalie R. Gassman, PhD received a BA in chemistry from Michigan State University. She earned a PhD from the University of California, Los Angeles, in chemistry. She held postdoctoral positions at the National Institute of Environmental Health Sciences and the Wake Forest University School of Medicine. Her postdoctoral training focused on the role of DNA repair in response to environmental exposures and how modulated DNA repair machinery contributes to cancer development. As an associate professor of pathology at the University of Alabama at Birmingham with joint appointments in Nutrition Sciences and at the O'Neal Comprehensive Cancer Center, her work focuses on characterizing how environmental exposures influence DNA repair and how DNA repair proteins are altered or modified in the context of cancer. She has developed a versatile detection method that can evaluate DNA lesions induced by environmental agents and help identify deficiencies in DNA repair mechanisms. Her research seeks to understand how the environment contributes to cancer development and how alterations in DNA repair pathways from environmental exposures give cancer cells a survival edge.

This seminar will be held in Grainger Hall room 1112 and online via Panopto.
Click "More Event Information" to visit the seminar website for a link to attend virtually.
Both attendance options are free and open to all.

Sponsor(s)
  • Nicholas School of the Environment
  • Integrated Toxicology & Environmental Health (ITEHP)
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